2/15/2023 0 Comments Aim assist download 1.78![]() At present, there is still no generally accepted procedure to structure, analyze, and interpret mechanistic studies in an efficient way ( Guyton et al. However, it is generally recognized that summarizing mechanistic data is challenging, in part because of the large diversity of study types and the high volume of available studies ( EFSA 2018). Mechanistic studies can be used to complement animal or epidemiological data to inform mechanisms of toxicity, dose–response assessment, and hazard identification ( National Academies of Sciences, Engineering, and Medicine 2017). Risk assessment of chemicals is commonly based on toxicological or epidemiological studies.
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